Weight loss and metabolic
The FDA-approved peptides for weight loss are semaglutide, tirzepatide and liraglutide, as shots and a pill. What else is sold, and what the trials show.
Where the category stands in May 2026 — what's available, who to trust, what costs what. 22-min read, medically reviewed.
Read the guideAn independent overview of the compounded-GLP-1 telehealth market and the providers we cover — market size, what the FDA changed, and an honest read on each.
View the provider overviewAll 17 reviewsPrimers for newcomers and deep dives for the curious. The foundation articles are published; more are in the pipeline.
View all Learn articlesWhat compounded and branded semaglutide and tirzepatide actually cost, from each provider's own published pricing.
Every peptide we cover, organized by what it actually does. Clinical evidence, regulatory status, and what to ask a licensed clinician — written for adults who want the honest version.
A to ZThe FDA-approved peptides for weight loss are semaglutide, tirzepatide and liraglutide, as shots and a pill. What else is sold, and what the trials show.
Melanocortin agonists, oxytocin, kisspeptin; libido and reproductive signaling pathways.
BPC-157, TB-500, KPV, GHK-Cu and the growth-hormone peptides sold for injury, muscle and sports recovery: the human trials behind each, and FDA status.
No peptide is FDA-approved for muscle growth. Ipamorelin, CJC-1295, MK-677 and the other growth-hormone boosters sold for it: the trials and WADA rules.
Peptides for anxiety, focus and memory: Selank, Semax, Cerebrolysin and Dihexa. None is FDA-approved; what the Russian and Western evidence shows.
Telomere, mitochondrial, and immune-related compounds; mostly research-stage outside Tesamorelin and Sermorelin.
Peptides for skin and hair growth: GHK-Cu, Argireline, Matrixyl and PTD-DBM. Which are cosmetic ingredients, which are drugs, and what the trials show.
| Compound | Category | Best for | Onset | |
|---|---|---|---|---|
| A | ||||
| AOD-9604 › Modified GH fragment | weight-loss | Targeted fat loss adjunct | 6-8 weeks | |
| Argireline › Acetyl hexapeptide-8 | skin-hair | Topical wrinkle reduction | 4-6 weeks | |
| B | ||||
| BPC-157Most read › Pentadecapeptide | recovery | Tissue repair, gut health | 1-2 weeks | |
| C | ||||
| Cerebrolysin › Brain peptide complex | cognitive | Neuroprotection (research-stage) | 3-4 weeks | |
| CJC-1295 › GHRH analog (long-acting) | performance | Sustained GH release | 3-5 weeks | |
| D | ||||
| Dihexa › Angiotensin IV analog | cognitive | Synaptogenesis (preclinical) | Preclinical | |
| E | ||||
| Epitalon › Tetrapeptide, pineal | longevity | Telomere / circadian | Cycle-based | |
| G | ||||
| GHK-Cu › Copper tripeptide-1 | skin-hair | Skin repair, collagen | 4-8 weeks | |
| GLP-1Most read › Incretin hormone & drug class | weight-loss | Class explainer — hormone, drugs, pipeline | Varies | |
| Glutathione › Tripeptide (γ-Glu-Cys-Gly) | longevity | Antioxidant; sold oral, IV and nasal | Varies | |
| I | ||||
| IGF-1 LR3 › IGF-1 analogue, 83 aa | performance | Lab research tool; no human data | No human data | |
| Ipamorelin › GH secretagogue | performance | Lean mass, recovery | 2-4 weeks | |
| K | ||||
| Kisspeptin › KISS1-derived | sexual-wellness | Reproductive hormone signaling | 1-4 weeks | |
| KPV › α-MSH(11-13) tripeptide | recovery | Inflammation (preclinical only) | No human data | |
| L | ||||
| Liraglutide › GLP-1 agonist | weight-loss | Weight loss (older generation) | 4-8 weeks | |
| M | ||||
| Matrixyl › Palmitoyl pentapeptide-4 | skin-hair | Collagen production (topical) | 6-12 weeks | |
| Melanotan II › α-MSH analog | sexual-wellness | Libido, pigmentation | 1-3 weeks | |
| MOTS-c › Mitochondrial-derived | longevity | Metabolic, mitochondrial | 4-6 weeks | |
| N | ||||
| NAD+ › Coenzyme (not a peptide) | longevity | Cellular energy, anti-aging | 2-4 weeks | |
| O | ||||
| Oxytocin › Nonapeptide | sexual-wellness | Bonding, intimacy | Acute | |
| P | ||||
| PT-141Most read › Bremelanotide | sexual-wellness | Desire (FDA-approved as Vyleesi) | 30-60 min | |
| PTD-DBM › Wnt pathway peptide | skin-hair | Hair regrowth (preclinical) | Preclinical | |
| R | ||||
| Retatrutide › GLP-1/GIP/glucagon triple agonist | weight-loss | Investigational — largest trial weight loss | Investigational | |
| S | ||||
| Selank › Heptapeptide | cognitive | Anxiolytic, focus | Days | |
| SemaglutideMost read › GLP-1 agonist (compounded) | weight-loss | Weight loss, blood sugar | 4-8 weeks | |
| Semax › ACTH(4-10) analog | cognitive | Focus, neuroprotection | Days | |
| SermorelinMost read › GHRH analog | longevity | Sleep, recovery, body comp | 4-6 weeks | |
| SS-31 › Tetrapeptide (elamipretide) | longevity | Mitochondria; approved for Barth syndrome | Varies | |
| T | ||||
| TB-500 › Thymosin Beta-4 fragment | recovery | Tissue repair, inflammation | 2-3 weeks | |
| Tesamorelin › GHRH analog (FDA-approved) | weight-loss | Visceral fat reduction | 8-12 weeks | |
| Thymalin › Thymus polypeptides | longevity | Immune restoration (research) | Cycle-based | |
| TirzepatideMost read › GLP-1/GIP dual agonist | weight-loss | Weight loss (dual agonist) | 4-6 weeks | |